Ground Zero

They've cut off a clear escape for you to go back, so you wisely run in the direction that's open in the opposite direction, while unleashing a burst of bullets just before your retreat.

The cannibal freaks run after you, while you attempt to figure out how to lose them, since their noises are starting to attract others.

When you manage to get out of sight of the horde, you see an open manhole you could enter, or you could just duck into one of the ruined buildings.