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Dr. Nefariousis The villain of Ratchet & Clank: Up Your Arsenal. Dr. Nefarious is a stereotypical robotic mad scientist who has a hatred for all organic life (or "squishies"), despite formerly being one himself. He and Qwark have a deep history going back to when they were in high school where Qwark, being bigger and older (he was 26, according to Nefarious), bullied and humiliated him. His plan was to use the Biobliterator, a superweapon that turns all organic life into robots, to convert all under his "benevolent, iron-fisted rule". In the end, he ends up getting stuck on an asteroid with his servant Lawrence, unable to get out of their location (for 5 to 10,000 years, according to Lawrence). He has a strange habit of overloading in times of extreme stress (specificly, when he sceams), causing him to freeze up and pick up random signals of a soap opera in his head, and the only way to get him out of this state is to smack him heavily in his head, which Lawrence calls 'The best part of his day'. It is apparent that Dr. Nefarious does not realize that he does this, for he never mentions it, and every time it happens he countinues screaming afterwards as if it never happened (Example: sceaming "QWAAAAAAA...", then freezing and picking up soap opera signals, then being smacked, and upon stopping, screaming "...AAAAAAARK"). Early on in Up Your Arsenal, it is also revealed that Nefarious is Clank's biggest fan, thinking that the Secret Agent Clank series are real. He does not appear to be very quick-witted, and his genius is commonly questioned by his stupid actions. He is clearly not proud of this. He makes a cameo appearance in Ratchet: Deadlocked alongside Lawrence still stuck on the same asteroid only to arrive at the ruins of the DreadZone Station. Nefarious reminded Lawrence that he said the two of them were coming within range of a space station. Lawrence said that they were, and questioning that how was he to know that it would suddenly explode.